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Dutch Study Links Diet Quality With IBD And IBS Symptoms

Could your diet be causing your digestive problems?

hplictawa@gmail.com' by Editorial Team
May 24, 2022
in Research
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Dutch Study Links Diet Quality With IBD And IBS Symptoms
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Medically reviewed by Onikepe Adegbola, MD, PhD 

Dutch Study Links Diet Quality With IBD And IBS Symptoms
Image by Katie Smith from Unsplash

A 2022 study from the Netherlands has revealed compelling correlations between diet quality and the symptoms and disease activity in inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). This study revealed that the diet quality in Dutch patients with IBD – especially with active IBD – or IBS, was inferior to that of healthy controls, as expressed by a decreased absolute intake of vegetables, fruits, and whole-grain products. 

This study titled “Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients” was published in Nutrients. Even more, this study found that an inferior diet quality had a different impact on IBD and IBS. In patients with IBD, poor diet quality was linked with both disease activity – as measured by the calprotectin levels – and the symptoms of abdominal pain. Whereas in patients with IBS, it was linked only with the symptoms of abdominal pain and reflux syndrome.   

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This study examined diet and disease characteristics in 238 patients with IBD (65.5% with Crohn’s disease and 34.5% with ulcerative colitis), 261 patients with IBS (21.5% with IBS-C, 35.6% with IBS-D, 39.5% with IBS-M, and 3.4% with IBS-U), and 195 healthy controls. 

What are the Major Implications of This Study?

This study confirms that diet quality is inferior in IBD and IBS patients, especially in those with active disease, which has been indicated in previous studies. 

IBS and IBD patients can make dietary adjustments to control their intake of symptom-triggering foods. This can cause a deterioration in their diet quality. In contrast, a low-quality diet can also be one of the causes of IBS and IBD. Low-quality diet may also be a trigger for active disease. Thus, the authors highlight that the correlations found in this study between symptoms and diet quality can be bidirectional. So, the cause and effect relations remain unclear in this study.  

Still, this study has some major implications. This study indicates that IBS and IBD patients need detailed dietary counseling and surveillance. This study also reinforces the need for further research on the relationship between diet and IBD/IBS.

What did the Authors of This Study Conclude?

The study authors concluded that some foods might be culprits in both IBS and IBD. Yet, the culprit foods may have different effects on IBD and IBS. While only symptoms could be affected in IBS, those with IBD may also affect disease activity as expressed by increased calprotectin levels. 

However, there is a need for more studies to examine the exact cause-effect relationship between diet and IBD/IBS. Nevertheless, IBS and IBD patients need dietary evaluation and counseling.  

Reference:

de Graaf, M., Spooren, C., Hendrix, E., Hesselink, M., Feskens, E., Smolinska, A., Keszthelyi, D., Pierik, M. J., Mujagic, Z., & Jonkers, D. (2022). Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients. Nutrients, 14(9), 1945. https://doi.org/10.3390/nu14091945

Tags: diet qualityIBDIBS
hplictawa@gmail.com'

Editorial Team

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A research paper was published in the Brazilian Journal of Biology, titled "Using Bifidobacterium and Propionibacterium Strains in Probiotic Consortia to Normalize the Gastrointestinal Tract." Based on expert opinions in the study, the microorganisms Bifidobacterium and Propionibacterium genera qualities can be preserved and encapsulated. This research backs up expert suggestions with clinical evidence, proving that the experts were correct. The gut microflora is responsible for regulating the body's activities and maintaining its health. Diabetes, obesity, inflammation, atherosclerosis, and other chronic diseases are due to dysbiosis. In the 2024 recommendations, experts recommended probiotics for living microorganisms that benefit the microflora and improve the health of the host organism helping prevent these diseases. Lactic acid bacteria from the Bifidobacterium and Propionibacterium genera are the frequent probiotics recommended. Bifidobacterium adolescentis-1909, Bifidobacterium longum infantis-1912, Propionibacterium jensenii B-6085, Propionibacterium freudenreichii -11921, Propionibacterium thoenii -6082, and Propionibacterium acidipropionici-5723 were examined for their probiotic characteristics in the study. This study was conducted in the Laboratory for Bio testing Natural Nutraceuticals at Kemerovo State University (Russia). The study used collection strains of the lactic acid bacteria Bifidobacterium adolescentis АС-1909, Bifidobacterium longum infantis АС-1912, Propionibacterium jensenii В-6085, Propionibacterium freudenreichiiВ-11921, Propionibacterium thoenii В-6082, and Propionibacterium acidipropionici В-5723. Lactic acid cultures were tested for antibacterial activity against the test cultures Salmonella enterica ATCC 14028, Staphylococcus aureusATCC 25923, Pseudomonas aeruginosa B6643, Proteus Vulgaris ATCC 63, and Listeria monocytogenes ATCC 7644. Additionally, the antibiotic resistance of lactic acid cultures was tested using the disk diffusion method. Bifidobacterium adolescentis-1909, Propionibacterium jensenii B-6085, and Propionibacterium thoenii 6082 showed moderate antibacterial activities against all test cultures. According to research, some Propionibacterium and Bifidobacterium strains, or their consortia, could be employed as probiotic cultures in dietary supplements or functional foods to prevent various chronic diseases like IBS. Why is this study important for patients with IBS Symptoms Although IBS is bothersome and inconvenient, it does not increase the chance of developing other health problems. However, the success of the treatment depends on what grade of IBS it is and how it is addressed. Bifidobacterium bacteria are particularly significant compared with other gut microbiota in probiotic cultures. Probiotics have a favorable effect in four ways. First, they produce antimicrobial compounds. Second, they are hostile to pathogenic and opportunistic strains. They also adhere to epithelial cells (cells of intestinal walls), posing a competitive threat to disease-causing bacteria. Finally, they inhibit the production of metabolites by pathogenic bacteria and cancer cells. What is the Key Takeaway from this Study Large doses of probiotics that contain these bacteria in dietary supplements or functional fermented milk products can stimulate their proliferation in the large intestine. The development of functional foods containing probiotics, particularly Bifidobacterium strains, is driven by the increased demand for health-beneficial foods. However, Propionibacterium 'dairy' strains have recently gained popularity. As a result, probiotic consortia of these species can be established to normalize the gastrointestinal microbiota's function. To preserve their quality, these microorganisms can be encapsulated (immobilized). All the strains can be employed to form various dietary supplements or functional product consortia.

A New Way To Improve Gut Health: Probiotic Consortia With Bifidobacterium And Propionibacterium Strains

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Dope Entrepreneurs is the hub for all dope gut health related content. We are a groundbreaking news publication dedicated to gut health. We cover gut health research, entrepreneurship, startups and the latest trends in gut health. We serve a growing segment of patients, entrepreneurs and investors who want to learn more about gut health, the disruption and market potential in this field, and how they can benefit from the latest advances in gut health. Dope entrepreneurs is led by Onikepe Adegbola, MD PhD DipIBLM, physician, scientist, and gut health entrepreneur.

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