Dope Entrepreneurs
  • Research
  • News
  • Articles
  • Reviews
No Result
View All Result
  • Research
  • News
  • Articles
  • Reviews
No Result
View All Result
Dope Entrepreneurs
No Result
View All Result
Home Research

Researchers Discover New Health Boosting Benefits of Vitamin K that Can Prevent Cell Death

mansibang.genese@gmail.com' by Genese Mansibang, RD
August 11, 2022
in Research
0
Vitamin K
2.8k
SHARES
6.3k
VIEWS
Share on FacebookShare on TwitterShare On Whatsapp

Researchers at Helmholtz Munich have discovered a new use for vitamin K, often recognized for its role in blood clotting. The scientists found that vitamin K in its fully reduced form functions as an antioxidant by effectively preventing ferroptotic cell death. Cellular iron plays a significant role in the natural cell death process known as ferroptosis, which is also characterized by the oxidative breakdown of cellular membranes. Additionally, the scientists determined that FSP1 is the long-suspected but unidentified warfarin-insensitive enzyme lowering vitamin K.

In recent years, ferroptosis has been linked to several illnesses, including Alzheimer’s disease and acute organ damage. Thus, the current findings suggest that vit. K therapy may be a fresh, effective method for treating these ferroptosis-related disorders.

 

ADVERTISEMENT

A Powerful Ferroptosis Suppressant

The inhibition of ferroptosis is seen to be a very promising strategy for treating many degenerative diseases, hence research into new mechanisms and substances that control ferroptosis is ongoing. Researchers from Tohoku University (Japan), University of Ottawa (Canada), and Technical University of Dresden (Germany), under the direction of Dr. Eikan Mishima and Dr. Marcus Conrad, both from the Institute of Metabolism and Cell Death at Helmholtz Munich, thoroughly examined several naturally occurring vitamins and their derivatives to identify these new molecules. Dr. Eikan Mishima, the study’s first author, said, “Surprisingly, we identified that vit. K, including phylloquinone (vitamin K1) and menaquinone-4 (vitamin K2), can efficiently rescue cells and tissues from undergoing ferroptosis” 

 

FSP1, a Highly Regarded Vitamin K Reducing Enzyme, Is Being Revealed.

Ferroptosis suppressor protein-1, also known as FSP1, was discovered as a new and potent regulator of ferroptosis by a research team led by Dr. Marcus Conrad in 2019. The study team has found that vitamin K hydroquinone, which has been reduced, functions as a potent lipophilic antioxidant and inhibits ferroptosis by capturing oxygen radicals in lipid bilayers. Furthermore, they discovered that FSP1 is the enzyme responsible for effectively reducing vit. K to vit. K hydroquinone, resulting in the activation of a brand-new, non-canonical vit. K cycle. The team went on to demonstrate that FSP1 is responsible for the vitamin K-reduction pathway being insensitive to warfarin, one of the most widely prescribed anticoagulants, given that vitamin K plays a crucial role in blood coagulation processes.

 

New Insights Into the Metabolism of Vitamin K

The final mystery surrounding vitamin K metabolism in blood clotting was resolved by identifying this enzyme, and the chemical basis for why vit. K serves as the antidote for warfarin overdose was clarified. As a result, Dr. Marcus Conrad explained that the findings link the two fields of ferroptosis research and vit. K biology and will serve as the foundation for the development of novel treatment options for disorders where ferroptosis has been involved. The researchers also postulate that vit. K may be one of the oldest forms of naturally occurring antioxidants because ferroptosis is most likely one of the oldest types of cell death. So, new facets of vitamin K’s function in life’s evolution are anticipated to emerge, according to Dr. Marcus Conrad

Tags: heathvitaminswellness
mansibang.genese@gmail.com'

Genese Mansibang, RD

Related Posts

Clinical Research Suggests Adding a Probiotic to the Diet for Those Dealing With Depression
Research

Clinical Research Suggests Adding a Probiotic to the Diet for Those Dealing With Depression

February 22, 2023
Clinical Research Data Indicates Gut Flora May Be Improved by the Antioxidant Characteristics of Beer Polyphenols
Research

Clinical Research Data Indicates Gut Flora May Be Improved by the Antioxidant Characteristics of Beer Polyphenols

February 22, 2023
FODMAP-Lowering Diet for IBS Patients
Research

FODMAP-Lowering Diet for IBS Patients

December 8, 2022
Next Post
Protein powder for women

Protein Powder For Women - Are They Right For You?

The Link Between Probiotics And Weight Loss

The Link Between Probiotics And Weight Loss

Benefits of Taking Digestive Enzymes

Benefits of Taking Digestive Enzymes

Follow Us

  • 9.9k Followers

Recommended

Study Confirms a Direct Relationship of Gut Microbiota with the Brain

Study Confirms A Direct Relationship Of Gut Microbiota With The Brain

3 years ago
Brief Comparison of Effective IBS Treatments

Brief Comparison of Effective IBS Treatments

3 years ago
Gut Virome Can Treat Intestinal And Immunological Diseases

Gut Virome Can Treat Intestinal And Immunological Diseases

3 years ago
Dietary Choices Are Influenced By Gut Microbiota

Dietary Choices Are Influenced By Gut Microbiota

3 years ago

Categories

  • Articles
  • General
  • News
  • Research
  • Reviews

Topics

acid reflux antibiotics bloating capsaicin causes coffee colonoscopy constipation Crohn's Disease deficiency diabetes diarrhea Digestive enzymes diverticulitis fatigue FODMAP gluten-free gut gut bacteria gut health gut microbiome gut microbiota health healthy diet IBD IBS IBS-C IBS diet inflammation inflammatory bowel disease irritable bowel syndrome lactobacillus low FODMAP diet microbiome microbiota probiotic probiotics quality of life research SIBO sucrose intolerance supplement tea therapy treatment
No Result
View All Result
https://casadesante.com https://casadesante.com https://casadesante.com

Highlights

Do Gallstones Cause Constipation? Gastroenterologist Explains

Does Pancreatitis Cause Gas & Bloating?

Sharp Liver Pain: 7 Causes & Mimics.

Does Your Liver Cause Pain After Eating?

Can You Get Gallstones After Having Your Gallbladder Removed?

When To Go To The Hospital For Gallbladder Attack?

Trending

General

6 Colon Cancer Symptoms In Women

by Editor
June 14, 2023
0

If you're a woman, it's important to be aware of the signs of colon cancer. In this...

Is It Normal To Have A Small Trace Of Bilirubin In Urine?

June 14, 2023

IBS Or Colon Cancer: Signs You Shouldn’t Ignore.

June 14, 2023

Do Gallstones Cause Constipation? Gastroenterologist Explains

June 14, 2023

Does Pancreatitis Cause Gas & Bloating?

June 14, 2023
dopelogo

Dope Entrepreneurs is the hub for all dope gut health related content. We are a groundbreaking news publication dedicated to gut health. We cover gut health research, entrepreneurship, startups and the latest trends in gut health. We serve a growing segment of patients, entrepreneurs and investors who want to learn more about gut health, the disruption and market potential in this field, and how they can benefit from the latest advances in gut health. Dope entrepreneurs is led by Onikepe Adegbola, MD PhD DipIBLM, physician, scientist, and gut health entrepreneur.

Categories

  • Research
  • News
  • Articles
  • Reviews
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms And Conditions


© 2022 Dope Entrepreneurs

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

No Result
View All Result
  • Research
  • News
  • Articles
  • Reviews

© 2022 Dope Entrepreneurs