Dope Entrepreneurs
  • Research
  • News
  • Articles
  • Reviews
No Result
View All Result
  • Research
  • News
  • Articles
  • Reviews
No Result
View All Result
Dope Entrepreneurs
No Result
View All Result
Home Research

You Probably Don’t Have IBS — Here’s Why

Could you have SIBO instead of irritable bowel syndrome?

hplictawa@gmail.com' by Editorial Team
May 7, 2022
in Research
0
You Probably Don’t Have IBS — Here’s Why
2.9k
SHARES
6.3k
VIEWS
Share on FacebookShare on TwitterShare On Whatsapp

Medically reviewed by Onikepe Adegbola, MD, PhD

GI Issues Symptoms

A study published in Scientific Reports, a Nature.com peer-reviewed journal, showed that 49% of patients diagnosed with irritable bowel syndrome (IBS) and referred to secondary care tested positive for small intestinal bacterial overgrowth (SIBO) instead.

ADVERTISEMENT

The same study found that people referred to secondary care diagnosed with IBS often have other non-cancerous gastrointestinal disorders, and needlessly suffer from conditions that could be treated if only they were properly diagnosed.

This study, “A systematic review and meta-analysis on the prevalence of non-malignant, organic gastrointestinal disorders misdiagnosed as irritable bowel syndrome,” was conducted by D. Poon, G. Law, G. Major, H. Jervoise, and N. Andreyevrty, focused on five organic gastrointestinal conditions, which doctors were misdiagnosing as IBS. The included disorders included bile acid diarrhea (BAD), carbohydrate malabsorption (CM), microscopic colitis (MC), pancreatic exocrine insufficiency (PEI), and small intestinal bacterial overgrowth (SIBO). The researchers retrieved the relevant data from the PubMed, EMBASE, and Cochrane medical databases from the years 1978 to 2020. The data were sorted and filtered for quality assurance purposes.

Using Q and I2 statistics, 2149 patients were included in a meta-analysis of 22 studies using a glucose breath test as a substrate (a foundation for the test). The crude pooled rate was 24.9% (range 0%–48.5%) and the estimated pooled rate was 19% (95% CI 13%–27%). This gives us a low range of 19% and a high of 25% of patients testing positive for SIBO.

Again, using Q and I2 statistics, this time, 4630 patients received a lactulose breath test in 36 studies as a substrate. The pooled rates for SIBO were 43.7% and 45.1% (range 0%–83.8%), respectively. The estimated pooled rates are 46% (95% CI 37%–55%) and 49% (95% CI 40%–57%). The lactulose section of the study included a group of patients who used six different diagnostic criteria to diagnose patients as positive for SIBO.

So, what is the takeaway from this meta-analysis of these studies? It is quite evident that patients presenting to either emergency care or their primary care physician with gastrointestinal symptoms are being misdiagnosed with IBS, and that in many cases an organic GI condition is to blame for their symptoms.

IBS is defined by what is known as a “cluster” of symptoms. The cluster has evolved over the years, but a diligent physician should have no problem diagnosing this disorder, which is marked by recurrent, defecation-associated abdominal pain. And when you consider that IBS affects 7%–21% of the global adult population, it is alarming to think that 49% of those people are going untreated when it is completely unnecessary.

The researchers in this study concluded that specialist-clinicians are too quick to diagnose IBS, and they question the current methods for diagnosing IBS in the ER and primary care settings. More research is needed to determine what it would cost to introduce more testing for people who present with IBS-like symptoms in the ER or primary care to avoid being misdiagnosed.         

References:

Dukowicz, A. C., Lacy, B. E., & Levine, G. M. (2007). Small intestinal bacterial overgrowth: a comprehensive review. Gastroenterology & hepatology, 3(2), 112–122.

Poon, D., Law, G. R., Major, G., & Andreyev, H. J. N. (2022, February 4). A systematic review and meta-analysis on the prevalence of non-malignant, organic gastrointestinal disorders misdiagnosed as irritable bowel syndrome. Nature News. Retrieved May 4, 2022, from https://www.nature.com/articles/s41598-022-05933-1#Sec1

Tags: GI issuesIBSmisdiagnosis of IBS
hplictawa@gmail.com'

Editorial Team

Related Posts

Clinical Research Suggests Adding a Probiotic to the Diet for Those Dealing With Depression
Research

Clinical Research Suggests Adding a Probiotic to the Diet for Those Dealing With Depression

January 10, 2023
Clinical Research Data Indicates Gut Flora May Be Improved by the Antioxidant Characteristics of Beer Polyphenols
Research

Clinical Research Data Indicates Gut Flora May Be Improved by the Antioxidant Characteristics of Beer Polyphenols

January 10, 2023
FODMAP-Lowering Diet for IBS Patients
Research

FODMAP-Lowering Diet for IBS Patients

December 8, 2022
Next Post
“IBS Patients Are Willing To Accept Significant Risks In Return For Cure Of IBS Symptoms” – A Recent UK Study

“IBS Patients Are Willing To Accept Significant Risks In Return For Cure Of IBS Symptoms” – A Recent UK Study

Predictive Markers For Microbiota In Gut Found In PIBD Patients On IFX Treatment

Predictive Markers For Microbiota In Gut Found In PIBD Patients On IFX Treatment

Inflammatory Bowel Disease Does Not Increase Risk Of Breakthrough Covid-19 Cases In Fully Vaccinated Patients

Inflammatory Bowel Disease Does Not Increase Risk Of Breakthrough Covid-19 Cases In Fully Vaccinated Patients

Follow Us

  • 9.9k Followers

Recommended

Study Confirms a Direct Relationship of Gut Microbiota with the Brain

Study Confirms A Direct Relationship Of Gut Microbiota With The Brain

10 months ago
Brief Comparison of Effective IBS Treatments

Brief Comparison of Effective IBS Treatments

10 months ago
Gut Virome Can Treat Intestinal And Immunological Diseases

Gut Virome Can Treat Intestinal And Immunological Diseases

10 months ago
Dietary Choices Are Influenced By Gut Microbiota

Dietary Choices Are Influenced By Gut Microbiota

10 months ago

Categories

  • Articles
  • General
  • News
  • Research
  • Reviews

Topics

acid reflux antibiotics bloating capsaicin causes colonoscopy constipation Crohn's Disease deficiency diabetes diarrhea Digestive enzymes diverticulitis fatigue FODMAP gluten-free gut gut bacteria gut health gut microbiome gut microbiota health healthy diet IBD IBS IBS-C IBS diet inflammation inflammatory bowel disease irritable bowel syndrome lactobacillus low FODMAP diet microbiome microbiota peppermint oil probiotic probiotics quality of life research SIBO sucrose intolerance supplement tea therapy treatment
No Result
View All Result
https://casadesante.com https://casadesante.com https://casadesante.com

Highlights

Science-Based Benefits Of Taking Digestive Enzymes For Efficient Digestive Healing

Association of Poor Vitamin and Mineral Intake to Irritable Bowel Syndrome Symptoms

A Systematic Review of the Linkage Between Irritable Bowel Syndrome and Macronutrients

Invitation To Colonoscopy Reduced Incidences Of Cancer But Not Death Through A Gold-Standard Trial

Symptoms, Causes, and Solutions to Vitamin B Deficiencies

A Meta-Analysis: The Diagnostic Yield Of Colonoscopy In IBS Patients For Organic Diseases

Trending

Clinical Research Suggests Adding a Probiotic to the Diet for Those Dealing With Depression
Research

Clinical Research Suggests Adding a Probiotic to the Diet for Those Dealing With Depression

by Ivy Totanes
January 10, 2023
0

A recently published scientific report from Basel, Switzerland, has demonstrated that probiotics can supplement antidepressant treatment. The...

Clinical Research Data Indicates Gut Flora May Be Improved by the Antioxidant Characteristics of Beer Polyphenols

Clinical Research Data Indicates Gut Flora May Be Improved by the Antioxidant Characteristics of Beer Polyphenols

January 10, 2023
FODMAP-Lowering Diet for IBS Patients

FODMAP-Lowering Diet for IBS Patients

December 8, 2022
Science-Based Benefits Of Taking Digestive Enzymes For Efficient Digestive Healing

Science-Based Benefits Of Taking Digestive Enzymes For Efficient Digestive Healing

October 25, 2022
Association of Poor Vitamin and Mineral Intake to Irritable Bowel Syndrome Symptoms

Association of Poor Vitamin and Mineral Intake to Irritable Bowel Syndrome Symptoms

October 18, 2022
Dope Entrepreneurs

Dope Entrepreneurs is the hub for all dope gut health related content. We are a groundbreaking news publication dedicated to gut health. We cover gut health research, entrepreneurship, startups and the latest trends in gut health. We serve a growing segment of patients, entrepreneurs and investors who want to learn more about gut health, the disruption and market potential in this field, and how they can benefit from the latest advances in gut health. Dope entrepreneurs is led by Onikepe Adegbola, MD PhD DipIBLM, physician, scientist, and gut health entrepreneur.

Categories

  • Research
  • News
  • Articles
  • Reviews
  • About Us
  • Contact Us
  • Privacy Policy
  • Terms And Conditions


© 2022 Dope Entrepreneurs

No Result
View All Result
  • Research
  • News
  • Articles
  • Reviews

© 2022 Dope Entrepreneurs

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist